A dielectric affinity glucose microsensor using hydrogel-functionalized coplanar electrodes

Functionalized Hydrogel on Plasmonic Nanoantennas for Noninvasive Glucose Sensing

Plasmonic nanostructures are intensely investigated as sensors due to their high sensitivity to changes in their nearest dielectric environment. However, additional steps have to be taken to provide specificity for a particular analyte. Here, gold nanoantennas are coated with a thin layer of a boronic acid functionalized hydrogel, which reversibly swells in the presence of glucose. This process...

Glucose-Sensitive Hydrogel Optical Fibers Functionalized with Phenylboronic Acid.

Hydrogel optical fibers are utilized for continuous glucose sensing in real time. The hydrogel fibers consist of poly(acrylamide-co-poly(ethylene glycol) diacrylate) cores functionalized with phenylboronic acid. The complexation of the phenylboronic acid and cis-diol groups of glucose enables reversible changes of the hydrogel fiber diameter. The analyses of light propagation loss allow for qua...

A Microfabricated Dielectric Affinity Sensor for Continuous Glucose Monitoring

We present a microfabricated affinity sensor using permittivity measurement for continuous glucose monitoring (CGM). This device is based on a perforated electrode separated from a bottom electrode on a substrate by a solution of a synthetic glucose-sensitive polymer. Glucose permeates through the perforated electrode and binds with the polymer, leading to a change in the polymer solution permi...

A Dielectric Affinity Microbiosensor

Diffraction grating of hydrogel functionalized with glucose oxidase for glucose detection.

A new sensing approach, employing diffraction gratings of hydrogel functionalized with glucose oxidase (GOx), was developed for quantitative glucose detection.